Chronic periodontal disease may contribute to diabetes, according to a review of recent research presented today. While it has been established that people with diabetes are more prone to developing periodontal disease, new research is suggesting that periodontal disease may, in turn, be a risk factor for diabetes. The research review was presented at an American Academy of Periodontology (AAP)/National Institute of Dental and Craniofacial Research (NIDCR) symposium on periodontal systemic connections in Bethesda, Md.
Periodontal disease can cause bacteria to enter the bloodstream and activate immune cells. These activated cells produce inflammatory biological signals (cytokines) that have a destructive effect throughout the entire body. Once this happens, it may induce Type 2 diabetes, even in otherwise healthy individuals with no other risk factors for diabetes," explained presenter Anthony Iacopino, D.M.D., Ph.D. in the Division of Prosthodontics at Marquette University's School of Dentistry in Milwaukee, Wis.
The next step to determine for sure whether or not periodontal disease can cause diabetes is to perform clinical studies and intervention trials, which answer the question, when periodontal disease is treated, does the risk for diabetes decrease? "Until we have results from intervention studies to better understand the role periodontal disease may play in diabetes, as well as heart disease, preterm births and respiratory disease, the best advice is for people to take excellent care of their oral health to help ensure they keep their teeth as well as maintain overall health," said Michael McGuire, D.D.S., president of the AAP.
Periodontal disease can cause bacteria to enter the bloodstream and activate immune cells. These activated cells produce inflammatory biological signals (cytokines) that have a destructive effect throughout the entire body. Once this happens, it may induce Type 2 diabetes, even in otherwise healthy individuals with no other risk factors for diabetes," explained presenter Anthony Iacopino, D.M.D., Ph.D. in the Division of Prosthodontics at Marquette University's School of Dentistry in Milwaukee, Wis.
The next step to determine for sure whether or not periodontal disease can cause diabetes is to perform clinical studies and intervention trials, which answer the question, when periodontal disease is treated, does the risk for diabetes decrease? "Until we have results from intervention studies to better understand the role periodontal disease may play in diabetes, as well as heart disease, preterm births and respiratory disease, the best advice is for people to take excellent care of their oral health to help ensure they keep their teeth as well as maintain overall health," said Michael McGuire, D.D.S., president of the AAP.
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